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Propose: To compare the safety and efficacy of hepatocellular carcinoma(HCC)with main portal vein tumor thrombus(MPVTT)treated by endovascular brachytherapy(EVBT)or three dimensional conformal radiotherapy(3-DCRT)after percutaneous transhepatic portal vein stenting and transarterial chemoembolization(PTPVS-TACE).