2. 您的位置
3. 首页
4. 会议论文
5. The adjuvant effects of N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride to a hepatitis A v

The adjuvant effects of N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride to a hepatitis A v

来源 :浙江省免疫学会第十次学术大会 | 被引量 : 0次 | 上传用户：liaotianeryi

【摘 要】

：

Objective: Chitosan is a biodegradable,biocompatible and natural polymer with low immunogenicity that derived from chitin through partial deacetylation.N-(2-hydroxypropyl)-3-trimethylammonium chitosan

【作 者】

：

Wei Tao Ting Fu Zhuojing He Ruxi Hu Lan Jia Yan Honga 

【机 构】

：

Institute of Bioengineering, Zhejiang Academy of Medical Sciences, 310013, 182 Tianmushan Road, Xihu

【出 处】

：

浙江省免疫学会第十次学术大会

【发表日期】

：

2016年8期

【关键词】

：

N-(2-hydroxy) propyl-3-trimethylammonium chitosan chloride vaccine hepatitis A v 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Objective: Chitosan is a biodegradable,biocompatible and natural polymer with low immunogenicity that derived from chitin through partial deacetylation.N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC) is a cationically modified chitosan.It has similar biological effects to non-modified chitosan.

其他文献

Expression of B7-H4 and hepatitis B virus X in hepatitis B virus-related hepatocellular carcinoma

AIM: To investigate the expression and clinical significance of B7-H4 and Hepatitis B virus X (HBx) protein in Hepatitis B virus-related hepatocellular carcinoma (HBV-HCC).METHODS: The expression of B

会议

Hepatocellular carcinomaHepatitis B virusHepatitis B virus XB7-H4Immunohisto

Klebsiella pneumoniae lipopolysaccharides induce TNF-α and IL-1β in macrophages via TLR 4-and 2-denp

Patients infected with Klebsiella pneumoniae are always lead to severe inflammatory response.However,little is known on the host cells pro-inflammatory response to this pathogen.Here we investigated t

会议

Klebsiella pneumoniaelipopolysaccharidesmacrophagespro-infla-mmatory cytokine

Analysis of the immunogenicity and bioactivities of a split influenza A/H7N9 vaccine mixed with MF59

Background: The H7N9 influenza virus caused significant mortality and morbidity in infected humans during an outbreak in China in 2013 and stimulated vaccine development efforts.As previous H7-based v

会议

TcpC inhibits the phenotypical and functional maturation of dendritic cells

Objectives: Toll/interleukin 1 receptor domain containing protein encoded by E.coli (TcpC) was found to be a virulence factor that promotes bacterial survival and is closely related to the pathogenesi

会议

E.coliTcpCDendritic cellsAntigen presentationPyelonephritis

Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/

In early spring 2013,human infections with a novel avian influenza A (H7N9) virus in Eastern China raised concerns of a new influenza pandemic.To address these concerns,the development of a safe and e

会议

Biological evaluation of antibody-maytansinoid conjugates as a strategy of RON targeted drug deliver

Background: Aberrant expression of the RON receptor tyrosine kinase,a member of the MET proto-oncogene family,in breast cancer and non-small cell lung cancer (NSCLC) has therapeutic implication.Here w

会议

Antibody-drug conjugateBreast cancerLung cancerReceptor tyrosine kinaseThera

p62在tamoxifen诱导子宫内膜癌变中的作用和机制

目的：乳腺癌是威胁妇女健康的主要恶性肿瘤,内分泌治疗是乳腺癌综合治疗的主要手段之一。他莫昔芬(Tamoxifen,TAM)一直是绝经前妇女乳腺癌辅助内分泌治疗的首选药物,但在其长期治疗过程中可能引起子宫内膜细胞的增殖及肥大,促进子宫内膜不典型增生、息肉甚至浸润性癌的形成,这在一定程度上影响了患者长期受益。但目前对TAM如何导致子宫内膜癌变的具体机制尚未完全阐明,我们将在此探讨p62在其中的可能作用

会议

二甲双胍联合索拉非尼对肝细胞肝癌的协同抑制作用

目的：索拉非尼是目前唯一经临床试验证实对晚期肝癌治疗有效的全身性药物，但其仅2-3个月的生存获益并不令人满意。本研究中，我们探索二甲双胍，目前作为Ⅱ型糖尿病的一线药物，是一种潜在的抗肝细胞肝癌的治疗药物。其与多靶点抑制剂索拉非尼可能发挥协同抑制肝细胞肝癌增殖及促进凋亡的作用。

会议

肝细胞肝癌二甲双胍索拉非尼mTORMAPK

Efficacy of Anti-RON Antibody Zt/g4-Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeu

Purpose: The receptor tyrosine kinase RON is critical in epithelial tumorigenesis and a drug target for cancer therapy.Here,we report the development and therapeutic efficacy of a novel anti-RON antib

会议

Clinical significance of inflammatory cytokine and chemokine expression in hand foot and mouth disea

Purpose: To determine the relationship of cytokine/chemokine expression with the clinical presentation of hand,foot and mouth disease (HFMD).Methods: This study involved 28 mild HFMD patients,44 sever

会议

Handfoot and mouth diseaseenterovirus 71inflammatory cytokineschemokines