目的: EML4-ALK fusion positive non-small cell lung cancer (NSCLC) patients benefit from crizotinib treatment.However, the fusion rate of different types of EML4-ALK and whether they have different clini
Objective: The purpose of the study was to evaluate the anti-proliferative activity and apoptotic effect of Gypsophila saponins on human gastric adenocarcinoma SGC-7901 cells and its mechanism.
Objective: Nicotine and its associated nicotinic acetylcholine receptors (nAChRs) are believed to be involved in the progression of some solid carcinomas by regulating cell proliferation, apoptosis, t
Objective: RHOC, as a member of the Ras superfamily of GTP-binding proteins, has been demonstrated to be involved in metastasis of many human malignancies;however, its role in human cholangiocellular
Objective: Pancreatic cancer is one of the most intractable and fatal cancer and biologically characterized by high degrees of hypoxia.Here, we describe PRMT5 (protein arginine methltransferase 5), a
Objective: Increased serum fibrinogen has been reported to be associated with tumor progression and a poor outcome in various carcinomas.However, the association between preoperative serum fibrinogen
Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide.Aberrant hepatocyte growth factor/MET signaling has been implicated in hepatocarcinogenesis, sug
Objective: Treatment options for older pts with R/R ALL are limited.Blinatumomab is a bispecific T-cell engager(BiTE(R)) antibody construct that directs cytotoxic T cells to CD 19-expressing B cells,
目的: Lung cancer is the leading cause of cancer-related deaths in China, currently, lun adenocarcinoma has become the major pathologic type of lung cancer.