Effect of carvedilol in attenuating the acute myocardium infarction-induced myocardial fibrosis in r

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：woaijiekexun

【摘要】

：

【作者】

：

Lin-qiu XIONG Zhi-xin SHAN Fu-yong HENG Zhu-jie NING Huang SHUAI Guo-lin LIN Zhang-meng ZHEN Deng-chun YU Yang MIN Yu-xi YONG

【机构】

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Division of Clinical Pharmacology,Guangdong Provincial Cardiovascular Institute,Guangdong General Ho

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

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carvedilol AMI extracellular matrix myocardial fibrosis

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Aim: Carvedilol, nonselective β-adrenoreceptor antagoruist, was shown protective effects against acute myocardium infarction(AMI)-induced myocardial injury,however, the mechanisms underlying the anti-fibrosis effect of carvedilol has not been well known.The aim of the present study was to investigate the potential mechanism for the anti-fibrosis effect of carvedilol against AMI-induced myocardial fibrosis in rat.

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Effect of carvedilol in attenuating the acute myocardium infarction-induced myocardial fibrosis in r

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