Rho-kinase相关论文
Fasudil inhibits platelet-derived growth factor-induced human pulmonary artery smooth muscle cell pr
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A Rho-kinase Inhibitor, Fasudil, Attenuates Progressive Glomerulosclerosis Induced by Daunorubicin i
Accumulating evidence suggests that the small G protein Rho and its downstream effector Rho kinase may play important ro......
Fasudil inhibits platelet-derived growth factor-induced human pulmonary artery smooth muscle cell pr
Background RhoA/ Rho kinase (ROCK) pathway is involved in pulmonary arterial hypertension (PAH) and pulmonary artery smo......
Downregulation of Rho associated coiled-coil forming protein kinase 1 in the process of delayed myoc
Background The connexln43 knockout (Cx43 KO) mouse dies at birth with an enlarged conotruncal region, which leads to the......
Effect of Rho-kinase pathway on neurite outgrowth of rat hippocampal neurons under atomic force micr
Hippocampal neurons of neonatal rats were cultured in serum-free culture medium for 5 days in vitro, and treated with th......
Downregulation of Rho associated coiled-coil forming protein kinase 1 in the process of delayed myoc
Background The connexln43 knockout (Cx43 KO) mouse dies at birth with an enlarged conotruncal region, which leads to the......
目的观察Rho激酶和转化生长因子β(transforming growth factor-β,TGF-β)通路是否参与醛固酮/氯化钠诱导的单肾切除SD大鼠肾脏损伤......
目的:探讨NOS/NO、HO/CO、RhoA/Rho激酶等信号通路在自发性高血压大鼠(SHR)阴茎海绵体中的表达及相互关系。方法:健康成年雄性SPF级SHR与......
目的观察Rho激酶(ROCKS)特异性抑制剂Y-27632对体外培养的U87胶质瘤细胞侵润能力的影响。方法体外培养U87胶质瘤细胞,采用Transwell......
目的通过Rho激酶(Rhokinase,ROCK)抑制剂干预急性冠脉综合征(acute coronary syndrome,ACS)患者,探讨其对血清白细胞介素37(interleukin-37......
目的:研究抑制Rho—kinase对柔红霉素诱导的肾小球硬化的调控作用,并探讨Rho—kinase抑制剂法舒地尔改善肾小球硬化的作用机制。方法......
目的:建立稳定的体外细胞缺氧模型,探讨人体脐静脉内皮细胞(HUVEC)在缺氧条件下RhoA蛋白和Rho激酶对其内皮细胞内皮型一氧化氮合酶(eNO......
研究背景心肌长时间缺血可以导致组织损伤以及细胞死亡,冠状动脉再通是缓解缺血损伤的关键,但较长时间缺血后的再灌注却可导致更为......
第一部分心肌缺血再灌注和缺血预适应中Rho-kinase对PI3-kinase/Akt的作用研究背景心血管疾病一直以来发病率居高不下,在心血管疾......
<正>Rho是小分子量GTPases超家族Rho亚家族成员,是Ras超家族的哺乳动物基因同系物。Rho可以通过其下游效应因子Rho激酶(Rock或Rho-......
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研究背景冠心病已成为我国城乡居民致死的主要原因之一,每年大约70万人死于冠心病,约占全部心血管病死亡的四分之一。再灌注疗法,......
目的:通过Western免疫印迹(Western blot)测定不吸烟的健康人、吸烟但肺功能正常人群、慢性阻塞性肺疾病(chronic obstructive pulm......
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