【摘 要】
：
Background: In this prospective,randomized,double-blind study,we verified the hypothesis that TEAS can alleviate remifentanil induced hyperalgesia in patients undergoing thyroidectomy.Methods: 60Ameri
【机 构】
：
Department of Anesthesiology,Fujian Provincial Hospital & The Shengli Clinical College of Fujian Med
【出 处】
：
中国中西医结合麻醉学会年会暨第二届全国中西医结合麻醉学术研讨会
论文部分内容阅读
Background: In this prospective,randomized,double-blind study,we verified the hypothesis that TEAS can alleviate remifentanil induced hyperalgesia in patients undergoing thyroidectomy.Methods: 60American Society of Anesthesiologists physical status(ASA)Ⅰ-Ⅱpatients,aged 18-60 year,scheduled for thyroidectomy were randomly allocated to TEAS or control groups.TEAS consisted of 30 min of stimulation(6-9mA,2/10Hz)on the Hegu(LI4)and Neiguan(PC6)before anaesthesia.Anesthesia was maintained with sevoflurane adjusted to bispectral index(40-60)and target remifentanil 5.0 ng/ml.Mechanical pain thresholds were assessed using electronic von Frey.The primary outcome was mechanical pain thresholds.Secondary outcomes included postoperative pain scores,the time to first rescue analgesic,additional analgesics and side effects.Results: Baseline mechanical pain thresholds were similar between two groups.The analysis revealed the reduction in mechanical threshold was greater in the control group than the TEAS group(P<0.001).Postoperative pain scores and cumulative number of rescue analgesia were lower in the TEAS group(P<0.05).In addition,TEAS group patients reduced the incidence of postoperative nausea,vomiting and shivering.Conclusion:Preoperative TEAS can attenuate remifentanil-induced hyperalgesia in patients undergoing thyroidectomy.
其他文献
Background and objective Opioids are very effective analgesics,and are still often used in postoperative pain therapy.How to enhance their analgesic effect and prevent their side effects is still a pr
目的：探讨CYP3A4基因检测对脊柱手术病人术后舒芬太尼合理用药的指导意义.方法：选取择期全麻下95例行后入路腰椎减压植骨内固定术的病人,山东籍,汉族,年龄20～60岁,ASA Ⅰ或Ⅱ级.采用聚合酶链反应-限制性片段长度多态性技术,进行CYP3A4基因检测,根据基因型将病人分为野生型纯合子、突变型杂合子组和突变型纯合子组.待病人清醒后行视觉模拟评分(VAS),当VAS超过3分时,则静脉间断给予舒芬
Patients with cervical spine instability usually present with limited range of neck motion and a challenged airway for tracheal intubation.1A special tracheal tube designed by Huafeng Wei named WEI Je
Background:Sevoflurane is widely employed for pediatric anesthesia since its beneficial pharmacological characteristics.However,the excitatory phenomenon is one of the main disadvantages during the in
Recent studies reported that 40%~84%patients suffered moderate to excruciating pain which maximum occurred during the first 12 h after surgery.Under treatment of postoperative pain after craniotomy ma
Background: Postoperative cognitive dysfunction(POCD)is a common neurological complication among the elderly after major surgery.
Background Postoperative pain is the main reason of the prolonging hospitalization and the dominating complaint.The traditional use of opioids and NSAIDs for postoperative analgesia causes a series of
Objectives: Fiberoptic intubation is a valuable modality for airway management.This study compared remifentanil and dexmedetomidine as anesthetics for modified Awake Fiberoptic Intubation(AFOI).Method
Background: Electroacupuncture(EA),a Chinese traditional therapy technique,was considered as an effective method for treating some painful neuropathy induced by various neuropathological damages.Howev
Background: We conducted this prospective,randomized,double-blind,placebo-controlled study to evaluates the effects of transcutaneous electric acupoint stimulation(TEAS)on the quality of recovery(QoR)