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5. New Concepts in Opioid Analgesic Drug Design

New Concepts in Opioid Analgesic Drug Design

来源 :第十三届中国国际多肽大会 | 被引量 : 0次 | 上传用户：asd010asd

【摘 要】

：

　　Currently used μ opioid analgesics(e.g.morphine)produce limiting side effects and are ineffective for treatment of neuropathic pain.Recent pharmacological

【作 者】

：

Peter W. Schiller 

【机 构】

：

ChemicalBiologyandPeptideResearch,ClinicalResearchInstituteofMontreal110PineAve.WestMontreal,Que.Can

【出 处】

：

第十三届中国国际多肽大会

【发表日期】

：

2014年6期

【关键词】

：

opioid analgesics/multifunctional peptide analogues/neuropathic pain/[Dmt1]DALDA 

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　　Currently used μ opioid analgesics(e.g.morphine)produce limiting side effects and are ineffective for treatment of neuropathic pain.Recent pharmacological evidence indicates that opioid compounds with bi-or multifunctional biological activity profiles may be superior analgesic drugs.

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