UNG1 Complexes in Oxidative Stress and DNA Repair

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：z492141756

【摘要】

：

【作者】

：

Yadong Hu Helin Wang Li Qiu Haiyun Deng Renshan Ge Haiteng Deng

【机构】

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MOE Key Laboratory of Bioinformatics,School of Life Sciences,Tsinghua University,Beijing,China

【出处】

：

第八届中国蛋白质组学大会

【发表日期】

：

2013年11期

【关键词】

：

DNA repair Oxidative stress UNG1 Protein complex SILAC Quantitative proteomics

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论文部分内容阅读

Deamination of cytosine or incorporation of dUMP during DNA replication leads to uracil incorporation and DNA damage.Uracil-DNAglycosylase (UNG) is a base excision repair enzyme that participates in repair of U/A pairs by cleaving the N-glycosylic bond andinitiating the base-excision repair (BER) pathway.

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UNG1 Complexes in Oxidative Stress and DNA Repair

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