论文部分内容阅读
Clinical pharmacokinetic analysis method of Iloperidone and its two main metabolites in human
【机 构】
:
Research Center for Drug Metabolism, College of Life Science, Jilin University, Changchun 130012, Ch
【出 处】
:
第十三次全国临床药理学学术大会
【发表日期】
:
2012年10期
其他文献
Deep understanding of the interaction between thienorphine and UDP-glucuronosyltransferase (UGT) iso
1.Thienorphine has been demonstrated to be a potent,long-acting partial opioid agonist.It is being developed as a good candidate to treat opioid dependence.2.The thienorphines glucuronide was detected
Aim:This study was conducted to assess the pharmacokinetic characteristics of cortisol in rats.Methods:Healthy male 12 SD rats were randomized to given 20mg·kg-1cortisol(F group) or cortisol combined
Trp64Arg polymorphism of β3-adrenergic receptor gene associated with hyperuricemia in a Chinese Male
Aim:Our aim was to determine the association of β3-adrenergic receptor gene Trp64Arg polymorphism with hyperuricemia in a Chinese male population.Methods:352 hyperuricemic and 420 normouricemic male s
会议
Influence of CYP2C19 loss-of-function variants on the antiplatelet effects and cardiovascular events
Background and Objectives A large number of clinical studies have well demonstrated that the loss-of-function variant allele CYP2C19*2 is associated with attenuated response to clopidogrel and increas
会议
Risk of adverse cardiovascular events with concomitant use of clopidogrel and proton pump inhibitors
会议
Comparative Fasting Bioavailability of Two Letrozole 2.5-mg Tablets in Healthy Chinese Postmenopausa
Background:Letrozole is an orally active aromatase inhibitor indicated for the treatment of postmenopausal women with breast cancer.Although the bioavailability and pharmacokinetic (PK) properties of
A new,rapid and sensitive method was developed for the quantifying of rhodamine 123 (R123) in rat plasma using liquid chromatography tandem mass spectrometry (LC-MS/MS).Rhodamine 6G (R6G) was used as
Development and validation of a new ultra performance liquid chromatographic method for the quantifi
An ultra performance liquid chromatographic (UPLC) method with photo-diode array (PDA) detection for the quantification of vancomycin in human serum was developed and validated.Protein precipitation w
会议
Pharmacokinetics and Safety of Ezetimibe/simvastatin Combination Tablet:An Open-label, Single-dose S
Background and objective:Ezetimibe/simvastatin combination tablet has been approved for the treatment of high LDL-C (Low-density-lipoprotein cholesterol) levels in patients with primary hypercholester
会议