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5. Increased oligomerization and phosphorylation of α-synuclein are associated with decreased activity

Increased oligomerization and phosphorylation of α-synuclein are associated with decreased activity

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：GYS876

【摘 要】

：

Aging is associated with an increased risk for Parkinsons disease(PD)and dementia with Lewy bodies(DLB),in which alpha-synuclein(α-syn)oligomerization plays key pathogenic roles.

【作 者】

：

Shun Yu Xin Li Weiwei Yang Peng Wang Xuran Li Xuying Li 

【机 构】

：

Department of Neurobiology,Xuanwu Hospital of Capital Medical University,Beijing,China;Center of Par

【出 处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

α-synuclein Parkinson’s disease dementia with Lewy bodies glucocerebrosidase cyn 

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　　Aging is associated with an increased risk for Parkinsons disease(PD)and dementia with Lewy bodies(DLB),in which alpha-synuclein(α-syn)oligomerization plays key pathogenic roles.

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