neuroinflammation相关论文
Advances in the knowledge on the role of apoptosis repressor with caspase recruitment domain in hemo
Theapoptosisrepressorwithcaspaserecruitmentdomain(ARC)playsacriticalroleinextrinsicapoptosisinitiationviadeathreceptorli......
Blood-retinal barrier as a converging pivot in understanding the initiation and development of retin
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CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR s
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Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic o
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Neuroinflammation and oxidative stress act in concert to promote neurodegeneration in the diabetic r
Diabetes is a lifelong disease characterized by glucose metabolic imbalance, in which low insulin levels or impaired ins......
Green tea catechins inhibit microglial activation which prevents the development of neurological dis
The over-activated microglial cells induce neuroinflammation which has the main role in neurological disorders. The over......
C/EBP β在神经炎症方面研究近年来成为热点,越来越多的研究表明,C/EBP β在神经炎症扮演重要角色,本文综述了C/EBP β在神经退行性疾......
Inhibition of extracellular vesicle pathway using neutral sphingomyelinase inhibitors as a neuroprot
Traumatic brain injury is a sudden trauma or blow on the head,and severe traumatic brain injury is a major cause of deat......
Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system by......
Previous studies have shown that Ninjurin-1 participates in cell trafficking and axonal growth following central and per......
Traumatic brain injury remains a global health crisis that spans all demographics, yet there exist limited treat-ment op......
The implication of the receptor for advanced glycation end-products (RAGE) in numerous diseases and neurodegenerative di......
In recent years,a type of extracellular vesicles named exosomes has emerged that play an important role in intercellular......
Identification of differentially expressed genes response to TCDD in rat brain after long-term low-d
Several cohort studies have reported that dioxin and dioxin-like polychlorinated biphenyls might impair the nervous syst......
Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced par
OBJECTIVE To evaluate these activities of Rg1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)/probenecid(MPTP/......
Inhibition of miR-873 provides therapeutic benefit in lipopolysaccharide-induced Parkinson disease a
OBJECTIVE Neuroinflammation plays a critical role in neurodegenerative disorders,although the inflammation may not the i......
CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR s
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
A new look at auranoifn, dextromethorphan and rosiglitazone for reduction of glia-mediated inlfammat
Neurodegenerative disorders including Alzheimer’s disease are characterized by chronic in-lfammation in the central ner......
Glaucoma is a chronic neurodegener-ative disorder characterized by progressive damage and loss of retinal ganglion cells......
目的:评价米诺环素对氯胺酮慢性暴露致小鼠认知功能障碍的影响。方法:健康雄性SPF级C57BL/6小鼠30只,21日龄,体重约23 g,分为3组(n=10):空白......
目的观察Nod样受体蛋白3 (Nod-like receptor protein 3, NLRP3)抑制剂MCC950对脓毒症相关性脑病(sepsis-associated encephalopat......
Sepsis-associated encephalopathy(SAE) is a brain dysfunction that occurs secondary to infection in the bo characterized ......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Microglia and astroglia: the role of neuroinflammation in lead toxicity and neuronal injury in the b
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Prenatal zinc supplementation to lipopolysaccharide infected female rats prevents neurochemical, beh
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Applying clustering coefficient to the pattern of international author collaboration in neuroimmunol
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Interactions between neurotropic pathogens, neuroinflammatory pathways, and autophagic neural cell d
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Temporal dynamic changes of connexin 43 expression in C6 cells following lipopolysaccharide stimulat
Connexin 43, a gap junction protein, is expressed mainly in glia in the central nervous system.Neuroinflammation plays a......
Cerebral neuroinflammation models were established by injecting 10 μg lipopolysaccharide into the hippocampus of male S......
脊髓损伤会造成严重的神经病理损害,且功能康复十分有限.最初的机械性损伤固然能迅速破坏神经元及神经胶质,但随后迟发的二次病理......
A new look at auranoifn, dextromethorphan and rosiglitazone for reduction of glia-mediated inlfammat
Neurodegenerative disorders including Alzheimer’s disease are characterized by chronic in-lfammation in the central ner......
目的 探讨miR-124对小胶质细胞分泌促炎细胞因子的调控作用及其机制. 方法 (1)用不同浓度梯度脂多糖(LPS)和不同时间刺激BV-2小胶......
过量锰暴露可能会损害中枢神经系统,产生不可逆转的神经毒性,导致严重的神经退行性疾病。锰的神经毒性机制可能与转运稳态失调、氧......
目的探究柚皮苷(naringin)对APPswe/PS1dE9双转基因小鼠小胶质细胞极化的调节效应及该效应对Aβ聚集和认知功能的影响。方法3月龄A......
小胶质细胞是神经系统免疫细胞,具有双重特性,既可以通过免疫反应增强吞噬能力、释放抗炎因子维持脑组织的稳态和保护神经元,又可......
目的:探讨莫诺苷对抑郁模型大鼠抑郁样行为和前额叶皮质核转录因子-κB(NF-κB)p65和白细胞介素(Interleukin,IL)-1β、肿瘤坏死因......
炎性衰老的核心机制归因于随衰老进程神经胶质细胞激活程度逐渐增加,慢性炎性逐步积累从而导致神经炎性水平呈进行性升高。研究利......
Plasmin is generally known as a promotor of inflammation.Recent advancement suggests that it has a complex role as immun......
目的:研究探讨中枢胶质细胞在炎症反应过程中, 转化生长因子β(TGFβ)-激活性激酶1(TAK1)诱导iNOS 表达的作用机制.方法:通过在胶......
流行病学和实验室研究已证明神经炎症与阿尔茨海默病(Alzheimer’s disease,AD)的发生发展密切相关,非甾体类抗炎药(nonsteroidal ......
神经炎症反应在脑损伤的发病机制中起重要作用。自噬是降解细胞内机能障碍的蛋白质和损伤的细胞器的关键生物学过程。自噬异常通过......
慢性脑低灌注(CCH)是血管性痴呆的危险因素之一,其相关机制涉及氧化应激、自噬、炎症反应等多个方面,其中神经炎症贯穿于CCH所致动......
为探讨2,2’,4,4’-四溴联苯醚(BDE-47)慢性暴露对脑顶叶皮质、海马和丘脑组织的影响及机制,小鼠经口腔灌胃20 mg·kg-1剂量的......
心肌梗死后抑郁障碍的发生使人们认识到心脑在病理上存在一定联系。患有急性心肌梗死患者具有三倍的风险发展为抑郁。反之,抑郁症状......
目的:探讨血小板活化因子受体拮抗剂银杏内脂B(BN52021)抑制细菌脂多糖诱导的脑内炎症反应的神经保护作用。方法:SD大鼠随机分为对照组......
目的:检测抑制受体相互作用蛋白1(RIP1)能否改善慢性应激导致的小鼠认知功能障碍。方法:C57BL/6J雄性小鼠随机分为对照组、对照+腹......