The aim of this study was to enrich and in vitro culture of the ovine spermatogonial stem cells(SSCs).Theappropriate age of the donor ram for SSCs isolation was investigated firstly.Spermatogonial ste
During mammalian embryonic development,DNA methylation and histone modifications are important in geneexpression regulation and epigenetic reprogramming.In cloned embryos,high levels of DNA methylatio
Wnt-Frizzled signaling is critical for neuronal development and disease.We have explored thecontribution of Frizzled receptor Fz8 to eye/retinal phenotypes in combination with Fz5. During retinaldevel