Pyrazoles constitute an important class of heterocyclic compounds exhibiting a wide range of biological activities[1] and they also act as vital building blocks of many pharmaceuticals and natural pro
质谱技术具有灵敏度高、特异好、普适性强等特点越来越成为最受青睐的现代分析测试技术之一.江西省质谱科学与仪器重点实验室研发的电喷雾萃取电离技术(EESI)[1]无需样品预处理即可以直接进行质谱分析,且数据重复性好,能够满足多变量统计分析的需要;此外,其电离区的独特设计也避免了待测物分子与高强电场的直接接触,是比ESI 更软的离子化方法,故利用EESI-MS 能够原位监测捕捉到有机反应过程中的反应物、
由于核磁共振波谱检测具有方便、简单、快速、环境友好等优点,同时随着小型化、微型化核磁共振的发展和普及,基于NMR 方法的手性识别及ee 值的测定越来越受到化学家的青睐[1],它能够观测到手性分子中每一个功能基团在手性识别过程中的表现,能清晰地表明主客体相互作用的位点,并且可以预测非对映体络合物的空间构象.一般说来,NMR 主要借助于化学位移、耦合常数、弛豫时间、NOE、扩散系数等参数来研究手性识别
As the CF3 group plays a conspicuous and increasingly important role within pharmaceuticals and agrochemicals,as well as in materials science,there has been a great deal of interest in developing effi
合成一系列50 种含C=N 桥键的芳基希夫碱对位-二取代苯亚甲基苯胺化合物p-X-C6H4CH=NC6H4-p-Y,测定其C=N 键的红外伸缩振动频率VC=N.
Density Functional Theory(DFT) at IDSCRF-B3LYP/DGDZVP computational level is employed to conduct theoretical study about reaction between o-carborane(R1a),n-butyllithium and N,N-diisopropylcarbodiimid
The infection disease caused by bacterial pathogens has become a major public health problem in recent years due to wide occurrence of drug resistance.
Natural products can be used as ideal lead structure to develop agrochemicals.β-Carboline and its saturated analogue are common structural motifs in natural products and pharmaceuticals.
Heterogeneous catalyst has the characteristics of high thermal stability,easy separation,recycling and so on [1-4].
The BN/CC isosterism has emerged as a powerful strategy to increase the chemical space of compounds relevant to materials science and biomedical research [1].