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5. SAE1 promotes human glioma progression through activating AKT SUMOylation and AKT signaling pathways

SAE1 promotes human glioma progression through activating AKT SUMOylation and AKT signaling pathways

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：hangcheng8351

【摘 要】

：

The SUMO-activating enzyme SAE1 involves in progression of several human cancers.However,its biological roles of SAE1 in glioma are unknown in previous research.In this study,we systematically investi

【作 者】

：

Yanfang Yang Ziwei Liang Xixi Wang Zenghua Sheng Shufang Liang 

【机 构】

：

State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,and Coll

【出 处】

：

中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

Glioma SAE1 SUMOylation Phosphorylation Akt signaling pathway 

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　　The SUMO-activating enzyme SAE1 involves in progression of several human cancers.However,its biological roles of SAE1 in glioma are unknown in previous research.In this study,we systematically investigate SAE1 associations with glioma progression in vitro and in vivo.

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