NHC-Catalyzed Annulation of 1H-Indol-2-yl-malonate with 2-Bromoenals:Enantioselective Synthesis of P

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：a15892465043

【摘要】

：

【作者】

：

Qi Liang-Liang Hui Xin-Ping

【机构】

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State Key Laboratory of Applied Organic Chemistry,College of Chemistry and Chemical Engineering,Lanz

【出处】

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中国化学会全国第十二届有机合成化学学术研讨会

【发表日期】

：

2015年7期

【关键词】

：

N-heterocyclic carbene 2-bromoenals annulation reaction

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　　Hydropyrido[1,2-a]indole is a core skeleton existing in a large class of naturally bioactive polycyclic indole alkaloids,such as mersicarpine,tronocarpine and(-)-strychnine.Therefore,much attention to construct such skeleton has been documented.1,2 NHC-catalyzed reactions are well developed and offer a broad range of unconventional transformations.

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NHC-Catalyzed Annulation of 1H-Indol-2-yl-malonate with 2-Bromoenals:Enantioselective Synthesis of P

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