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  5. Antidepressant effect of Xiaochaihutang in the unpredictable chronic mild stress model via increasin

Antidepressant effect of Xiaochaihutang in the unpredictable chronic mild stress model via increasin

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：LYXTTKX
【摘 要】
：
Aim: Xiaochaihutang (XCHT) has been used in China for thousands of years to treat "Shaoyang syndrome", which involves depressive-like symptoms.Previous studies in our laboratory have showed that XCHT
【作 者】
：
Guang-yue SU Jing-yu YANG Fang WANG Jie MA Kuo ZHANG Cui SONG Huan-huan PANG Ying-xu DONG Chun-fu WU 
【机 构】
：
Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
XCHT CUMS BDNF TrkB hippocampus 
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Aim: Xiaochaihutang (XCHT) has been used in China for thousands of years to treat "Shaoyang syndrome", which involves depressive-like symptoms.Previous studies in our laboratory have showed that XCHT produced antidepressant-like action in rodent behavioral despair models.The present study was aimed to investigate the mechanism(s) underlying the antidepressant-like effect by measuring brainderived neurotrophic factor (BDNF) and its primary receptor tropomyosin-related kinase B (TrkB) in rat hippocampus.
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