论文部分内容阅读
【目的】通过对12年来中心NICU中超低出生体重儿(extremely low birth weight infant,ELBWI)的生存状况分析,探讨ELBWI的生存质量及相关干预措施。【方法】对本院新生儿病房NICU自2000年2月-2012年1月的32例ELBWI进行回顾性分析。【结果】12年来ELBWI存活率34.4%,病死率25.0%,放弃率40.6%,辅助生育的ELBWI均积极治疗,存活率75.0%。所有存活者中女性占72.7%,明显高于男性。直接死亡原因最常见肺出血(62.5%),其次为早产儿肺透明膜病(12.5%)、颅内出血(12.5%)及消化道穿孔(12.5%)。将病例分为前、后两阶段(2000年2月-2006年1月和2006年2月-2012年1月)比较,后阶段放弃率明显低于前阶段(28.0%和85.7%),存活率明显高于前阶段(44%和0%);将病例分为存活组和死亡/放弃组比较,单因素及Logistic回归分析均显示辅助生育可能影响死亡率(P<0.05)。【结论】医患同盟积极救治,及时处理并发症,有助于提高ELBWI存活率,降低病死率;对处于生存极限的ELBWI的救治应权衡利弊,并注意提高ELBWI生活质量。
【Objective】 To investigate the quality of life of ELBWI and related interventions by analyzing the survival status of ELBWI in NICU in 12 years. 【Methods】 A retrospective analysis of 32 ELBWI cases from NICU of our hospital from February 2000 to January 2012 was conducted. 【Results】 The ELBWI survival rate was 34.4%, the mortality rate was 25.0% and the abandonment rate was 40.6% in 12 years. ELBWI assisted treatment was actively treated with a survival rate of 75.0%. Women accounted for 72.7% of all survivors, significantly higher than men. The direct cause of death was the most common pulmonary hemorrhage (62.5%), followed by hyaline membrane disease (12.5%), intracranial hemorrhage (12.5%) and digestive tract perforation (12.5%) in preterm infants. The cases were divided into two phases (February 2000-January 2006 and February 2006-January 2012). The abandonment rate of the latter stage was significantly lower than that of the previous stage (28.0% and 85.7%), and survival Rates were significantly higher than those of the previous stage (44% vs 0%). The cases were divided into survival group and death / abandonment group. Both univariate and logistic regression analysis showed that assisted reproduction may affect the mortality rate (P <0.05). 【Conclusion】 Active treatment and timely treatment of complications by the medical staff and patients alliance help to improve the ELBWI survival rate and reduce the mortality rate. To treat the extremity ELBWI should weigh the pros and cons and pay attention to improve the ELBWI quality of life.