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OBJECTIVE: This study aimed to detect insulin-like growth factor-1 (IGF-1), homocysteine (HCY), high sensitive C-reaction protein (hs-CRP), lipoprotein-a (Lp(a)), uric acid (UA) and the lipid of related index (TCH, TG, hdl-c, LDL-C) of level changes, and to discuss their clinical application of the correlation between Butylphthalide capsule and drug analysis.