【摘 要】
：
Ovarian cancer patients usually have poor prognosis due to late diagnosis and relapse with chemoresistance.It is therefore desirable to exploit new agents and novel targets for ovarian cancer treatmen
【机 构】
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Department of Molecular Medicine and Genetics and Ministry of Education Key Laboratory of Experiment
【出 处】
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2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议
论文部分内容阅读
Ovarian cancer patients usually have poor prognosis due to late diagnosis and relapse with chemoresistance.It is therefore desirable to exploit new agents and novel targets for ovarian cancer treatment.Berberine has been shown to have antitumor activity against various types of tumor cells.In this study, we assessed the antitumor effect of berberine on ovarian cancer cells in vitro and in vivo.Berberine exhibited a lower IC50 value than cisplatin on HEY and A2780ovarian cancer cells while having lower toxicity to non-malignant fallopian tube epithelial cells.
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