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  5. Preparation and characterization of pH-Sensitive Dextran Nanoparticle

Preparation and characterization of pH-Sensitive Dextran Nanoparticle

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：zhaoguopu
【摘 要】
：
One of challenge for cancer therapy is efficient delivery of anticancer agents into tumor sites to increase the efficiency of drugs and reduce the side effects.The natural dextran (DEX) as a potential
【作 者】
：
Bi Wang Peng Liu Jihua Gao Ping Gong 
【机 构】
：
College of Materials Science and Engineering,Shenzhen University,Shenzhen 518060,PR China;Guangdong
【出 处】
：
International Conference on Nanoscience & Technology,China 2
【发表日期】
：
2013年3期
【关键词】
：
Dextran pH-sensitive drug delivery Nanoparticles 
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　　One of challenge for cancer therapy is efficient delivery of anticancer agents into tumor sites to increase the efficiency of drugs and reduce the side effects.The natural dextran (DEX) as a potential drug carrier, which is bioeompatible, biodegradable and non-immunogenic, could load hydrophobic drugs effectively, prolong circulation in the bloodstream and accumulate passively in tumor tissues by the enhanced permeability and retention (EPR) effect.
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