论文部分内容阅读
Recently, we found that the cardiovascular effects of adenosine, insulin and Ang Ⅱ in the nucleus tractus solitarii (NTS) were attenuated by nitric oxide synthase (NOS) inhibitors.We reported the cardiovascular effects of NO, insulin, adenosine and Ang Ⅱ and their molecular signaling pathways in the NTS in this report.Our studies first demonstrated that adenosine may phosphorylate eNOS through activation of ERK in the NTS.Evidence indicates that adenosine-ERK-eNOS signaling pathway related to the production of NO in the regulation of BP in the NTS.