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  5. Dual-stimulus-responsive crosslinking chitosan as a gene vector

Dual-stimulus-responsive crosslinking chitosan as a gene vector

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：kayeyoo
【摘 要】
：
Stimulus-responsive gene vectors,that release gene in response to endosomal pH or cytoplasmic glutathione (GSH) have attracted increasing interests in tumor therapy[1,2].Developing gene-delivery syste
【作 者】
：
Huiying Chen Shubiao Zhang Xiaojun Peng 
【机 构】
：
Key Laboratory of Biotechnology and Bioresources Utilization,The State Ethnic Affairs Commission-Min
【出 处】
：
Fourth Symposium on Innovative Polymers for Controlled Deliv
【发表日期】
：
2016年11期
【关键词】
：
Chitosan stimulus-responsive gene vectors acylhydrazone disulfide 
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　　Stimulus-responsive gene vectors,that release gene in response to endosomal pH or cytoplasmic glutathione (GSH) have attracted increasing interests in tumor therapy[1,2].Developing gene-delivery systems responsive to pH or GSH responsive in intracellular compartments gives a resolution to improve the efficiency of tumor-targeted gene therapy.
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