Smart polymer microspheres with environmental sensitivity and magnetic orientation are interesting carriers for controlled drug release,and have extensive applications in targeted cancer treatment.β-cyclodextrin with a special structure of a hydrophilic exterior and a lipophilic cavity can form stable inclusion complexes [1].In recent years,the preparation and modification of β-cyclodextrin microspheres,either single or dual stimuli-responsive to be used as drug carriers has obtained a lot of attention.