【摘 要】
：
Objective: To explore the Influence of insulin determir combined with repaglinide therapy on serum uric acid of newly diagnosed type 2 diabetic patients.Methods: A total of 36 newly diagnosed type 2 d
【机 构】
：
Department of Endocrinology, Affiliated Xiaogan hospital of Wuhan University of Science and Technolo
论文部分内容阅读
Objective: To explore the Influence of insulin determir combined with repaglinide therapy on serum uric acid of newly diagnosed type 2 diabetic patients.Methods: A total of 36 newly diagnosed type 2 diabetic patients withHbA1c≥8.5％ received insulin determir combined with repaglinide therapy for 12 weeks.A comparison on serum uric(UA),fasting plasma glucose(FPG),2h postprandial glucose(2hPG),glycosylated hemoglobin A1c(HbA1c),blood lipid,body weight,fasting insulin(FINS),homa-insulin resistance(Homa-IR)and insulin sensitivity index(ISI) were performed before and after the treatment.
其他文献
目的 探讨儿童非典型溶血尿毒综合征(aHUS)的临床特点及转归预后。方法 对2007年12月至2015年5月在温州医科大学附属育英儿童医院住院明确诊断且资料完整的11例aHUS患儿的临床资料、实验室检查、治疗及转归进行回顾性分析。
系膜增生性肾小球肾炎(MsPGN)是一组以弥漫性肾小球系膜细胞增生及不同程度系膜基质增多为主要特征的原发性肾小球疾病,可导致肾小球硬化及肾间质纤维化,以血尿、蛋白尿、高血压、肾功能不全及肾小管间质损害等为临床表现.本文通过全方与不同拆方亚组间的对比,研究对MsPGN模型大鼠肾组织血小板源性生长因子-β(PDGF-β)、纤维连接蛋白(FN)的影响,以探讨肾系康方的作用机制.
目的：评价灌胃给予健脾生血颗粒浸膏对大鼠胚胎-胎仔发育的毒性作用.方法：孕鼠随机分为阴性对照组、阳性对照组和低、中、高剂量试验组,分别于孕期第6天至第15天连续灌胃给药.其中,低、中、高剂量试验组分别灌胃健脾生血颗粒浸膏1.16、3.48、10.44 g/kg/d,阳性对照组灌胃维生素A醋酸酯0.08g/kg/d,阴性对照组给予同样体积的纯净水.记录孕鼠的体重、身长、摄食量及临床表现.于妊娠第20
儿童哮喘是小儿的常见病、疑难病，该病严重的影响了儿童的生存质量，并有逐年增多的趋势.本文探索平哮汤对支气管哮喘豚鼠NO和IL-4的影响.实验方法：选择健康幼龄雄性豚鼠40只，将豚鼠随机分为4组，即哮喘模型组、平哮汤组、地塞米松片对照组，正常对照组.采用卵蛋白造模方法.实验观察：1、平哮汤对哮喘模型豚鼠引喘潜伏期的影响.2、平哮汤对哮喘模型豚鼠血清中一氧化氮(NO)的影响.3、平哮汤对哮喘模型豚鼠支
目的 射干2号合剂针对小儿实证、热证居多,适用小儿外感风热痰热为主的咳嗽,根据多年临床经验,不断改进.该研究观察射干2号口服液治疗小儿过敏性咳嗽与对照组的疗效比较.方法 选择过敏性咳嗽小儿共150例,病例按2∶1被随机分配到试验组和对照组.试验组服用射干2号合剂,对照组服用急支糖浆(由太极集团涪陵制药厂出品).1号合剂(射干2号合剂)：1-5岁,10ml/次,每日2次；5-12岁,10ml/次,每
Heart failure is a leading cause of morbidity and mortality in the USA and is closely associated with diabetes mellitus.The molecular link between diabetes and heart failure is incompletely understood
The genetic etiology of adult-onset autoimmune diabetes and especially a ent autoimmune diabetes in adults (LADA) remains unresolved.LADA exhibits features of both type 1 (T1D) and type 2 (T2D) diabet
Brown fat can reduce obesity through the dissipation of calories as heat.Control of thermogenic gene expression occurs via the induction of various co-activators,most notably PGC-1α.In contrast, the t
Animal models have contributed enormously to study in the field of type 1 diabetes (T1D).Discovered in the late 1970s, NOD mouse has become necessary in the study of T1D and provided researchers impor
Objective: To characterize the histone H3 differentially acetylated gene profiles between patients with latent autoimmune diabetes in adult (LADA) or classical type 1 diabetes (TA) and normal controls