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Danhong injection (DHI), a Chinese Materia Medica standardized product extractedfrom Radix Salviae miltiorrhizae and Flos Carthami tinctorii, is effective in the treatment of atherosclerosis (AS)-related diseases.It is widely recognized that AS is a complex inflammatory disease of the arterial wall and the dendritic cells (DCs) is a major player in the pathogenesis of AS via mediating atherosclerotic antigen presenting and T lymphocytes.Here, we determined the ef-fect and possible mechanism of DHI on oxidized low-density lipoprotein (ox-LDL)-induced matu-ration and immune function of DCs.