【摘 要】
:
Background:The initiation of angiogenesis can mark the transition from tumor dormancy to active growth and recurrence.Mechanisms that regulate recurrence in human cancers are poorly understood,in part
【机 构】
:
The Obstetrics & Gynecology Hospital of Fudan University,Shanghai 200011,China
【出 处】
:
生殖与发育医学进展探索2014上海研究生学术论坛
论文部分内容阅读
Background:The initiation of angiogenesis can mark the transition from tumor dormancy to active growth and recurrence.Mechanisms that regulate recurrence in human cancers are poorly understood,in part because of the absence of relevant models.
其他文献
蛋白尿不仅是肾功能进行性恶化的独立危险因素,也是导致ESRD的重要原因。目的:本文基于前期对导师周恩超教授益气祛风法理论的回顾和总结,通过临床观察,评估益气祛风法治疗CKD1-3期非肾病范围蛋白尿的疗效。方法:将入组病例随机分为治疗组和对照组,治疗组给予基础治疗(A)、益气祛风方(B)和临证加减(C)处理,对照组给予A+C+D(D:常规辨证论治),对比两组治疗前后24hU-TP、Hb、Alb、Sc
目的:探讨和验证老师在临床实践中总结出的益肾解毒法结合长程间歇灌肠治疗慢性肾脏病(Chronic kidney disease,CKD) 3-4期的经验及临床疗效观察.方法:简明阐述周师对于"肾劳"等相关疾病的病因病机的认识.临床观察病例60例,分为治疗组及对照组,对照组予中药煎剂口服,治疗组加用排毒泄浊汤煎剂保留灌肠,每周三次,3月为一疗程,共2个疗程.定期观察两组患者中医证候改变情况,以及实验
目的 探讨益肾解毒法中药多剂型干预CKD4-5期的临床疗效.方法 选择我科门诊就诊的CKD4-5期患者17例,给予中药多剂型给药方案干预,对患者治疗前后临床症状、血肌酐水平、eGFR进行分析评估,探讨干预效果.结果 本组17例患者治疗后平均症状积分为(1.59±1.50),明显低于治疗前平均症状积分(4.88±2.62),p<0.01;治疗后平均血肌酐值数值明显下降,eGFR与治疗前比较显著上升,
目的:在理论研究及临床实践的基础上,观察三黄益肾颗粒对气阴两虚、血瘀湿浊证的糖尿病肾病Ⅳ期患者的治疗效果.方法:使用中药三黄益肾颗粒和西药厄贝沙坦,基于糖尿病肾病Ⅳ期患者,进行多中心随机对照研究.结果:研究纳入病例56例,治疗组27例,对照组29例.两组均可改善中医证候总积分(P<0.01),治疗组优于对照组;治疗组可显著改善24小时尿蛋白定量(P<0.05),综合疗效评定有效率92.6%,优于对
目的:探讨糖尿病肾病(DN)患者血清晚期氧化蛋白产物(AOPP)、脂类代谢、N-乙酰-β-D-葡萄糖苷酶(NAG)的临床意义及中药补脾肾活血法治疗糖尿病肾病的机制. 方法:80例糖尿病肾病患者采用随机数字表分为中药治疗组(60例)和对照组(20例),另从住院或门诊体检选择15例健康对照组(NC).中药治疗组按照国际统一诊断标准(Mogensen诊断分期标准)及血清肌酐分为早期糖尿病肾病组(DN1组
Objective:To explore the relationship between metabolic abnormalities and DPE (disordered proliferative endometrium),EH (endometrial hyperplasia) and type Ⅰ EC (endometrial cancer).
Objects:Nitric oxide (NO) is highly unstable and has a half-life of seconds in buffer solutions.It is synthesized by NO-synthase (NOS) which has been found to exist in the following three isoforms:neu
Objects:Aberrant aufophagy has been suggested to play a role in endometriosis and thus to involved in apoptosis of endometrial stromal cells (ESCs).However,the potential mechanismsthat regulate autoph
Objects:To evaluate biochemical changes in vivo in premature ovarian insufficiency (POI) mice induced by Tripterygium glycosides (TG) and to explore the possible pathogenesis of POI induced byTG.
目的:Piwil1在生物发育过程中维持干细胞的功能并且在许多肿瘤中发挥癌基因功能.本研究旨在探讨Piwil1在子宫内膜癌的发生发展中是否发挥重要作用.方法:使用免疫组化方法检测Piwil1在正常子宫内膜(44例)、不典型增生的子宫内膜(17例)及子宫内膜癌中(83例)的表达.分别使用Piwil1表达质粒和Piwil1干扰质粒建立Piwil1上调或下调的细胞稳转株.通过MTT、平板克隆实验、tran