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5. Human monocyte-targeted non-viral siRNA delivery for the suppression of inflammatory macrophages

Human monocyte-targeted non-viral siRNA delivery for the suppression of inflammatory macrophages

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：gg42201

【摘 要】

：

Antibodies have been applied for the development of targeted gene delivery systems.Single chain antibodies targeting Herceptin and EGFR delivered siRNAs to cancer cells specifically and suppressed tum

【作 者】

：

Seok-Beom Yong Jee Young Chung Hyung Jin Kim Jang Kyoung Kim Yong-Hee Kim 

【机 构】

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Department of Bioengineering,Hanyang University,04763 Seoul,Korea

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

monocyte targeting single chain antibody gene silencing inflammatory diseases 

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　　Antibodies have been applied for the development of targeted gene delivery systems.Single chain antibodies targeting Herceptin and EGFR delivered siRNAs to cancer cells specifically and suppressed tumor growth in mice models[1,2].

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