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Neuroplastin 65 (NP65) Is a Brain-Specific and Glycoprotein Highly Existed in Synaptic Membranes, and Its Function Needs to Be Explored.NP65 (-/-) C57BL/6 Mice Were Obtained By Gene Targeting.The Present Results Showed that: Firstly, the Cultured Hippocampal Neurons from NP65(-/-) Mice Expressed only MAP-2 but not NP65.