Structure-based drug discovery and design for novel small molecular inhibitors of Sphingomyelin synt

来源 :全国药物化学学术会议暨第四届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：qmdx521

【摘要】

：

Aim To discover novel small molecular inhibitors of sphingomyelin synthase(SMS)as a tool to study the biological function of sphingomyelin synthase and as a lead compound for new preventive and therap

【作者】

：

LI Ya-li DENG Xiao-dong WANG Ren-xiao JIANG Xian-cheng ZHOU Lu YE De-yong

【机构】

：

Department of Medicinal Chemistry,School of Pharmacy,Fudan University,Shanghai 201203,China

【出处】

：

全国药物化学学术会议暨第四届中英药物化学学术会议

【发表日期】

：

2013年11期

【关键词】

：

sphingomyelin synthase point mutagenesis structure-based drug design virtual scr

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Structure-based drug discovery and design for novel small molecular inhibitors of Sphingomyelin synt

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