目的 初步探寻分析环甲关节的不对称性形成原因。方法 38具尸体(中国人男性15例,女性5例；新西兰人男性11例,女性,7例。年龄范围57～95岁,平均年龄为74岁),采用大体解剖方法进行喉部取材后,去除环甲关节周围软组织,定义环状软骨板正中矢状面和甲状软骨板后缘及下角的长轴之间的角度为环甲角,利用Image J软件(NIH, USA)测量,并对喉标本左右侧、不同性别、不同人群的环甲角值差异进行统计
Background: The medial wall of the cavernous sinus is believed to play a significant role in determining the direction of growth of pituitary adenomas and in planning pituitary surgery.However, it rem
Adeno-associated virus (AAV) mediated gene transfer has been demonstrated to be an effective approach for treating Parkinson s disease (PD).Triptolide T10 is a monomeric compound isolated from tripter
Survival after acute myocardial infarction is decreased in elderly patients.The enhanced rates of apoptosis in the aging heart exacerbated myocardial ischemia/reperfusion (MI/R) injury.We have recentl
The age-related loss of antioxidant defense reduces the recovery from myocardial ischemia/reperfusion injury (MI/R) in aged people.Our previous data showed inactivation of thioredoxin (Trx) was involv
Oxidative stress and inflammation as the pathoogical components of Alzheimer s disease (AD) have been well understood.Among a diversity of mitogen-activated proein kinase (MAPK) family members, JNK an
Objectives This study investigated the correlation between changes in angiotensin Ⅱ type 1 receptor agonistic autoantibody (AT1AA) and aldosterone (ALD) in preeclampsia (PE).Background Impaired ALD ge
Extracellular cysteine (Cys)/cystine (CySS) redox potential (Eh) has been shown to regulate diverse biological processes, including enzyme catalysis, gene expression, and signaling pathways for cell p
目的 证明酪氨酸激酶受体(KIT)在小鼠胃肠黏膜上皮的表达,并探讨其可能作用。方法 应用免疫荧光、Western blot和RT-PCR等技术检测KIT在野生型C57BL/6小鼠,以及乙基亚硝酸钠(ENU)诱变的c-kit基因点突变小鼠(纯合子)证明KIT胃肠黏膜上皮的表达；腹腔注射5-溴脱氧尿嘧啶核苷(BrdU)(30 mg/kg)观察实验小鼠结肠黏膜上皮BrdU掺入情况及动态变化,分析KIT在
目的 研究小胶质细胞对不同类型神经元引发的炎症反应,来探讨多巴胺能神经元的选择性受损原因,进一步明确帕金森病的发病机制。方法 用磁珠分选法分离纯化原代小胶质细胞,检测小胶质细胞与MN9D细胞插件培养后不同时间点细胞系的抑制率,并记录MN9D细胞形态变化。同时检测小胶质细胞与不同类型细胞系共培养炎症因子的释放。结果 脂多糖(lipopolysaccharide,LPS)刺激激活的小胶质细胞抑制了MN