【摘 要】
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LINGO-1 is a Leucine rich repeat, Ig domain-containing, Nogo receptor Interacting protein, selectively expressed in the CNS on both oligodendrocytes and neurons.Its expression is developmentally regul
【机 构】
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Distinguished Investigator in Discovery Neurobiology Biogen Idec USA
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LINGO-1 is a Leucine rich repeat, Ig domain-containing, Nogo receptor Interacting protein, selectively expressed in the CNS on both oligodendrocytes and neurons.Its expression is developmentally regulated, and is up-regulated during CNS diseases and injury.In animal models, LINGO-1 expression is up-regulated in rat spinal cord injury, EAE and glaucoma.
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