Effects of promoters,the Woodchuck hepatitis post-transcriptional regulatory element,and weakened se

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：kuang25748

【摘要】

：

Chinese hamster ovary(CHO)cells are the host of choice for the production of recombinant proteins in mammalian expression systems.Here,we investigated the effects of promoters,the Woodchuck hepatitis

【作者】

：

Tian-Yun Wang Wen Wang Si-Jia Chen Qin Li Fang Wang Li Wang Xian-Jun Yang

【机构】

：

Department of Biochemistry and Molecular Biology,Xinxiang Medical University,Xinxiang 453003,Henan,C

【出处】

：

中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

Chinese hamster ovary WPRE Promoter Weakened Resistance gene Transgene

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　　Chinese hamster ovary(CHO)cells are the host of choice for the production of recombinant proteins in mammalian expression systems.Here,we investigated the effects of promoters,the Woodchuck hepatitis posttranscriptional regulatory element(WPRE),and selection markers on transgene expression in CHO cells.

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