• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. A Sparse-land Model-based Approach for Gene Network Reconstruction

A Sparse-land Model-based Approach for Gene Network Reconstruction

来源 :第七届全国生物信息学与系统生物学学术大会 | 被引量 : 0次 | 上传用户：ultizen
【摘 要】
：
Reconstruction of gene regulatory networks (GRNs) is of utmost interest to biologists and is vital for understanding the complex regulatory mechanisms within the cell.The outcome of the current algori
【作 者】
：
Ming Shi Zhi-Zhun Huang Hong-Qiang Wang 
【机 构】
：
Machine Intelligence and Biomedical Bigdata Lab., Hefei Institutes of Physical Science,Chinese Acade
【出 处】
：
第七届全国生物信息学与系统生物学学术大会
【发表日期】
：
2016年8期
【关键词】
：
Gene Regulatory network Key Regulators Sparse Representation Dictionary Learning 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Reconstruction of gene regulatory networks (GRNs) is of utmost interest to biologists and is vital for understanding the complex regulatory mechanisms within the cell.The outcome of the current algorithms highly depends on the completeness of the datasets,and the performance may be greatly degraded due to the missing information about some key regulators.
其他文献
The link between dynamic modes of p53 and cell-fate decision in the DNA damage response
p53 shows stimulus-dependent dynamics in the DNA damage response,and the dynamic modes of p53 is linked closely with the decision making between cell fates.On one hand,we developed a network model to
会议
p53 dynamicscell fatebistabilityDNA damage response
Visualization of P wave characteristics of abnormal ECG signals
Discussed the visualization of the ECG signal based on the variable value measurement system,and made a comparison between the routine ECG and the ECG scatter point map for the diagnosis of P wave ano
会议
ElectrocardiogramP wave ECG signalVariable value visualization research
Establishment and Analysis of Avian Genome Evolutionary Tree
Birds are the most species-rich class of tetrapod vertebrates[1].In all kinds of ecological environment,about 10,000 kinds of bird species distribute in the earth.Because the birds have experienced a
会议
Bird genomeEvolutionary tree
Tracking the Genetic Evolution of Zika Virus
The current epidemic of Zika virus (ZIKV) in the Americas is particularly alarming given its confirmed neuropathological associations,such as fetal microcephaly and Guillain-Barre syndrome.As most of
会议
Zika virusPhylogenetic analysisSNPEvolution
JNCO: A jointly norm constrained optimization to identify both recurrent and individual copy number
Motivation: Recent studies have illustrated association between copy number variations (CNVs) and particular tumor types.By the help of different high-throughput technologies,such as array-based compa
会议
NeuroPP: a web service for predicting neuropeptide precursor
Background: Neuropeptides (NPs) play critical roles in synaptic signaling in various systems.NPs act as hormone,modulator,neurotransmitter and cytokine to regulate broad functions.NPs share the common
会议
neuropeptide precursorpredictorfeature optimizationsupport vector machine
Integrating multi-dimensional genomic data to identify core gene modules and cooperative networks in
Due to the extensive complexity and high genetic heterogeneity of genetic alterations in cancer,comprehensively depicting the molecular mechanisms of cancer remains difficult.Characterizing functional
会议
Somatic alterationTumor stratificationModulesIntegrative method
RNA-QC-Chain: Comprehensive and fast quality control for RNA-Seq data
RNA-Seq has become one of the most widely used applications based on next-generation sequencing (NGS) technology.However,raw RNA-Seq data may have various quality issues,which can significantly distor
会议
RNA-SeqQuality ControlParallel Computation
THANATOS: an integrative data resource of proteins and post-translational modifications in the regul
Autophagy is a highly conserved process for degrading cytoplasmic contents,determines cell survival or death,and regulates the cellular homeostasis.Besides core ATG proteins,a large number of regulato
会议
autophagypost-translational modificationphosphorylationprotein kinasecell de
Discovery of hub module and prediction of gene function based on weighted gene co-expression network
Background: Recently,the prediction of gene function has become a hot issue and various methods have been used to predict system-levels function of genes.Within those feasible methods,gene co-expressi
会议
WGCNAHub moduleGene functionPrediction