Hepatic stellate cell (HSC) plays a key role in pathogenesis of liver fibrosis.During liver injury, hypoxia and inflammation in local micro-environment migh
Baicalein (BA), one of the major compounds isolated from the root of Scutellaria baicalensis Gerogi, is a bioactive flavonoid with various pharmacological e
Platycodin D (PD) is the main saponin isolated from the traditional Chinese herb Platycodon radix.It exhibits anticancer activity in several types of cancer
Rab proteins are key regulators of cellular trafficking.Rab5 and Rab7 are endocytic Rab proteins functioning in modules to regulate vesicle trafficking from
ZNF32 is a recently identified zinc finger protein and its functions remain largely unknown.Autophagy has been shown to affect cell proliferation and surviv
Autophagy is an intracellular process of uptaking and degrading cytoplasmic organelles and other materials.It is a conserved degradation pathway among all e
Introduction.Mechanosensory osteocytes (OYs) are the most abundant and long-lived (up to decades) cells entombed in bone.The longevity of osteocytes is achi
Autophagy is a dynamic process accomplished by the generation and maturation of autophagosomes.Isolation of autophagosomes and subsequent compositional anal
Dyslipidemia, a principal symptom of the metabolic syndrome and diabetes mellitus, exposes the heart to elevated circulating levels of fatty acid (FA).