【摘 要】
：
Recombinant monoclonal antibodies can be heterogeneous due to modifications that can occur during expression, purification or storage.These large multi-chai
【机 构】
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Scientist Protein Analytical Chemistry Genentech Inc. USA
论文部分内容阅读
Recombinant monoclonal antibodies can be heterogeneous due to modifications that can occur during expression, purification or storage.These large multi-chain proteins are structurally challenging for detailed characterization to identify the sites of modifications.Mass spectrometry has played key roles in assessing protein primary structure with high degree of details.
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