【摘 要】
：
Background Increasing evidence indicates that Th17 cells play a potential role in asthma, especially in severe asthma.Dopamine D1-like receptor (D1-like-R) antagonist could suppress Th17 cell differen
论文部分内容阅读
Background Increasing evidence indicates that Th17 cells play a potential role in asthma, especially in severe asthma.Dopamine D1-like receptor (D1-like-R) antagonist could suppress Th17 cell differentiation.
其他文献
胸腔积液的形成是由于胸腔液体的入量多于出量造成的,其机制包括:肺毛细血管压增高(如充血性心力衰竭)、血管通透性增高(如肺炎)、胸腔内压力变小(如肺不张)、血浆胶体渗透压降低(如低蛋白血症)、胸膜通透性增高及淋巴液的循环受阻(如胸膜恶性肿瘤或感染)、隔下炎症(如肝脓肿)、以及胸导管破裂(如乳糜胸)等.
全球哮喘防治指南(GINA)将哮喘定义为一种"慢性气道炎症性疾患".近年的研究都证实哮喘是一种有明显异质性(heterogeneity)的疾病.这种异质性使哮喘从气道炎症机制、病理生理和临床表现等方面都可以分为一些不同的表型(Phenotypes).
国际上第一个关于特发性间质性肺炎(IIP)的专家共识是2002年由美国胸科学会(ATS)和欧洲呼吸病学会(ERS)共同制定的,该共识将IIP根据肺脏病理学表现分为7大类,即寻常型间质性肺炎(UIP)(对应的临床诊断为特发性肺间质纤维化,IPF)、非特异性间质性肺炎(NSIP)、隐源性机化性肺炎(COP)、脱屑性间质性肺炎(DIP)、呼吸性细致气管炎并间质性肺炎(RB-ILD)、淋巴细胞性间质性肺炎
Background Intravenous and intratracheal implantation of mesenchymal stem cells (MSCs) may offer ameliorating effects on pulmonary hypertension (PH) induced by monocrotaline (MCT) in rats.
Background The p38 MAPK signaling pathway plays a prominent role in the pro-inflammatory cytokines biosynthesis.Our previous studies showed that p38 MAPK is activated in aged murine lungs with a corre
Background IL-25 (also termed as IL-17E), is a special member of IL-17 family, which is closely linked to asthma.It contributes to the pathogenesis of asthma through enhancing expression of IL-4, IL-5
E-cadherin contributes critically to the architecture and immunological function of airway epithelium, which plays an essential role in asthma pathogenesis.
Background It has not yet reached an agreement over the mechanism of ventilator induced lung injury (VILI), which is commonly attributed to the application of excessive tidal volume (volutrauma), airw
Background miR-122 is a serum signature for liver injury and a prognostic predictor for sepsis patients.Sepsis patients with coagulation abnormalities may be a major impact on the outcome.
In the present study, we explored the effects of demethylation on lung function, lung cell apoptosis and the cytochrome c oxidase (COX) activity in a cigarette smoke-induced emphysema/chronic obstruct