Background: More recently, mast cells have been depicted in their potential to boost mucosal vaccination as mast cell activators are demonstrated to be powerful mucosal adjuvants.There are two phenoty
Background: Discovery of F protein expressed from the HCV core coding sequence challenges properties assigned to core protein, however, little is known about its correlation between evolution of HCV s
Most cell types have the capability to sense and respond to the physiological fluid flow-derived shear stress (SS).Dendritic cells (DCs) are the most powerful professional antigen-presenting cells as
Background : The naturally acquired human immunity to malaria is in some way defective or short-lived.Objective: We have investigated the kinetics, duration and characteristics of the Plasmodium-speci
细菌等病原体侵人体内后,可以被巨噬细胞吞噬消灭,也可以经巨噬细胞抗原提呈后启动适应性免疫应答.在巨噬细胞对病原体的免疫应答过程中巨噬细胞可以向不同的方向极化.在急性感染性疾病中,巨噬细胞以M1型极化为主,M1型巨噬细胞主要作用是促进炎症和杀灭细菌的作用;在慢性感染性疾病中,巨噬细胞以M2型极化为主,M2型巨噬细胞的主要作用是调节炎症.巨噬细胞的极化可以影响感染性疾病的发展,病原体也可以影响巨噬细胞
Background: Homotypic cell aggregation plays important roles in physiological and pathological processes, including embryogenesis, immune responses, angiogenesis, tumor cell invasion and metastasis.CD
In order to obtain a certain length(630bp) of constant domain gene, a pair of primer was designed according to the conserved nucleotide sequence of gallus(EU477527.1) and Taeniopygia guttata (XM_00218
Background: To investigate the relationship between the level of plasma homocysteine (Hcy) and carotid artery plaques in patients with acute cerebral infarction (ACI).Methods: 100 patients with ACI we
研究背景:肺间质纤维化是一种慢性的、渐进的肺间质疾病,其特点是大量积累细胞外基质,重塑肺结构,并伴随着严重的关节炎等并发症.在肺间质纤维化发生发展过程中,巨噬细胞、Th17细胞及一些其他淋巴细胞都起到非常关键的作用.研究表明,在人或鼠的肺纤维化过程中,CD147的表达会上升,但是CD147在肺纤维化中的具体作用机制还不清楚.
Sepsis is one of the most challenging clinical problems worldwide, and constitutes the leading cause of death in many intensive care units.Sepsis-associated prolonged immunosuppression of innate and a