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Background:This study investigated whether an imbalance in Th1/Th2 ceils is involved in the post-resuscitation myocardial dysfunction.Methods:After pigs were subjected to 8 min of electrically-induced cardiac arrest,animals in the post-return of spontaneous circulation (ROSC) group were randomly assigned to be sacrificed (n =8 per group) at 12 and 24 h after ROSC.CD4+ and CD8+ lymphocyte subsets were determined by flow cytometry,IL-4 and IFN-γ in the myocardium were measured by ELISA,.and protein and mRNA levels of GATA-3 and T-bet were detected in the myocardium by western blotting and quantitative real-time PCR,respectively.