【摘 要】
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Endochondral bone formation is largely dependent on cartilage lineage cells.The chondrocytes in growth plates continuously undergo a sequential process from proliferation to terminal hypertrophic diff
【机 构】
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State Key Laboratory of Proteomics, Genetic Laboratory of Development and Diseases, Institute of Bio
论文部分内容阅读
Endochondral bone formation is largely dependent on cartilage lineage cells.The chondrocytes in growth plates continuously undergo a sequential process from proliferation to terminal hypertrophic differentiation.Once differentiated, hypertrophic chondrocytes elicit multiple functions such as determining bone length, inducing osteogenesis as well as directing bone mineralization, and eventually disappear at the chondro-osseous junction.
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