【摘 要】
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Arylamines and their derivatives play an important role in biological active compounds,functional materials as well as organic synthetic intermediates.1-3 Thus the development of facile and efficient
【机 构】
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School of Materials and Chemical Engineering, Hubei University of Technology, Wuhan 430068
【出 处】
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中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
Arylamines and their derivatives play an important role in biological active compounds,functional materials as well as organic synthetic intermediates.1-3 Thus the development of facile and efficient methods for constructing aromatic C-N bonds has attracted substantial attention.In recent years,N-fluorobenzenesulfonimide (NFSI) has received increasing attention and been disclosed as a nitrogen source for amination of aromatic,heteroaromatic,benzylic,and allylic C-H bonds.4An oxidative C-H amination of 8-acylaminoquinolines and anilides with N-fluorobenzenesulfonimide (NFSI) have been developed,which was only mediated by a hypervalent iodine reagent PhI(OPiv)2 without any metallic catalyst or oxidant.The protocol showed good air and moisture tolerance,functional groups compatibility,and gave the highly site-selective amination products in moderate to good yields,which would provide a novel and facile methodology for synthesis of arylamine compounds.
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