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目的:探讨原发性高血压与良性前列腺增生(BPH)发生与临床进展的相关性。方法:将确诊为良性前列腺增生的78例BPH患者分为单纯性BPH组和BPH合并有高血压组两组,其中BPH组33例,BPH合并有高血压组45例。对两组患者的尿流率、残尿量、血清前列腺特异性抗原(PSA)、血尿发生率、前列腺体积、国际前列腺症状(IPSS)评分、尿潴留次数及不稳定膀胱发生率指标进行对比分析。结果:两组患者间在年龄、尿流率、残尿量、PSA、最大膀胱容量及最大逼尿肌压力指标差异无统计学意义(P>0.05)。而BPH合并高血压患者在血尿发生率、前列腺体积、IPSS评分、尿潴留次数及不稳定膀胱发生率指标上明显大于单纯良性前列腺增生组,差异有统计学意义(P<0.05)。结论:原发性高血压患者发生前列腺增生的病例报道越来越多,高血压状态能够促进BPH的发生以及临床进展。
Objective: To investigate the relationship between primary hypertension and benign prostatic hyperplasia (BPH) and its clinical progress. Methods: Seventy-eight BPH patients diagnosed as benign prostatic hyperplasia (BPH) were divided into two groups: BPH group and BPH group, including 33 BPH patients and 45 BPH patients. The urinary flow rate, residual urine volume, serum PSA, hematuria, prostate volume, IPSS score, urinary retention and unstable bladder incidence were compared between the two groups . Results: There was no significant difference in age, urine flow rate, residual urine volume, PSA, maximum bladder volume and maximal detrusor pressure between the two groups (P> 0.05). BPH with hypertension in patients with hematuria incidence, prostate volume, IPSS score, urinary retention frequency and unstable bladder was significantly higher than the indicators of benign prostatic hyperplasia group, the difference was statistically significant (P <0.05). Conclusion: There are more and more reports of benign prostatic hyperplasia in patients with essential hypertension. Hypertension can promote the occurrence of BPH and its clinical progress.