【摘 要】
：
Polymeric micelles as drug carriers play a vital role in the treatment of a broad spectrum of malignancies.Recently,reactive oxygen species (ROS)-responsive drug delivery systems have attracted a grea
【机 构】
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Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education,School of C
【出 处】
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Fourth Symposium on Innovative Polymers for Controlled Deliv
论文部分内容阅读
Polymeric micelles as drug carriers play a vital role in the treatment of a broad spectrum of malignancies.Recently,reactive oxygen species (ROS)-responsive drug delivery systems have attracted a great deal of attention,which is mostly due to the fact that cancer cells can generate a lot of intracellular ROS,including H2O2,superoxide (Of) and hydroxyl radical,in comparison with normal cells[1].However,the application of traditional ROS-responsive nanoparticles is limited due to their burst drug release in the blood circulation and slow release in the tumor tissue[2].
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