NDV对NF-κB和IRF7信号通路影响的研究

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户:blogbee
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病毒的感染与致病是病毒因素和宿主因素相互作用的结果,既有病毒为逃避宿主防御机制而进行的改变,也有宿主为清除病毒而调动固有免疫体系迅速产生效应分子和免疫效应,构建机体抵御病毒入侵的生物防线.IFN调节因子(interferon regulation factor,IRF)家族在IFN的诱导表达中起着重要的调节作用,近来研究表明IRF-7是诱导IFN表达的最主要的调节因子.
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