Th2相关论文
目的探究anti-Ex160抗体是否能够有效抑制家兔肝脏中虫卵内毛蚴的成熟,减轻肝脏纤维化的程度,并进一步阐述其机制。方法家兔分为6......
目的:探讨黄芪多糖对糖尿病肾病(DN)患者肾功能、外周血中性粒细胞/淋巴细胞比值(NLR)、Th1、Th2及Th1/Th2值的影响.方法:选取DN患......
血吸虫可通过合成、分泌或者排泄多种具有免疫调节功能的分子影响宿主的免疫系统,主要表现为促进Th2免疫效应,抑制Th1/Th17免疫效......
目的:探究分析急性放射性口腔黏膜炎患者CD4+/CD8+、Th1、Th2、Th17表达水平及其临床意义.方法:选取2017年10月-2020年10月揭阳市......
目的 探讨深度水解乳清蛋白配方奶(eHF-w)和标准早产配方奶(SPF)对早产儿外周血中免疫细胞的影响.方法 采用前瞻队列研究的方法,纳......
期刊
目的:探讨小青龙汤对鸡卵清白蛋白(Albumin from chicken egg white, OVA)诱导的变应性鼻炎(Allergic rhinitis,AR)小鼠的治疗作用及对IL-......
目的:观察艾灸对肉瘤微环境中Th1细胞、Th2细胞和Th1/Th2漂移的影响.方法:SPF级C57BL/6J小鼠随机分为空白组、模型组、顺铂组和艾......
目的 使用网络药理学方法筛选连翘治疗特应性皮炎的作用靶点,探索其治疗特应性皮炎的作用机制.方法 使用中药系统药理学数据库与分......
Objective:To evaluate the involvement of different CD4+ T cell subtypes in the anti-asthmatic effects of acupuncture in ......
期刊
Background: Rheumatoid arthritis (RA) is one of the most common autoimmune diseases worldwide, pathologically characteri......
目的 Sarcoidosis is a systemic inflammatory disorder characterized by granulomas.Not enough evidences correlate the dera......
IL-33 aggravates DSS-induced acute colitis by up-regulation of Th2 cytokine production in lamina pro
Objectiv: Interleukin-33 (IL-33) is a member of the IL-1 family.Its receptor, T1/ST2 (ST2), a member of the IL-1 recepto......
会议
Basophil detection in rheumatoid arthritis patients and its relationship with disease activity and t
Objective: To investigate the activation state of peripheral basophils from RA patients and its mechanism, and the relat......
Decidual CD56brightCXCR4+ natural killer cells induce maternal-fetal immune tolerance via an interle
Successful pregnancy requires maternal immune system to tolerate the semi-allogeneic fetus.Th2 dominant cytokines and re......
Preventive effects of andrographolide on the development of diabetes in autoimmune diabetic NOD mice
Aim: Andrographolide, as an active component in traditional anti-diabetic herbal plants, is a diterpenoid lactone isolat......
IL-33 alleviate DSS-induced chronic colitis by suppressing Th1/Th17 cytokine production in lamina pr
Objectiv: Interleukin (IL)-33, belonging to the IL-1 cytokine family member, is an important modulator of the immune sys......
Lysine Monomethylation is Critical for IRF4-Mediated Transcriptional Regulation of Th2 Lineage Commi
Interferon regulatory factor 4 (IRF4) regulates the transcription of genes essential for the differentiation and functio......
目的:探讨HIV/AIDS 患者外周血中CD4+T 细胞亚群及中性粒细胞CD64 的变化。方法:筛选2014 年5 月至9 月河南中医学院第一附属医院艾......
干扰素调节因子4(IRF4)通过转录调控细胞分化核心转录因子及分泌型细胞因子表达,从而介导体内多种天然免疫细胞如树突状细胞和巨噬......
TBX21 polymorphisms are associated with virus persistence in hepatitis C virus infection patients fr
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and the varied outcomes of the infection dep......
Galectin-9/Tim-3 interaction induces maternal-fetal immune tolerance via regulating peripheral blood
Tim-3 is well known to interact with its natural ligand, Galectin9, to dampen Th1 immunity and promote peripheral tolera......
Th1, Th2 and Th17 associated cytokines expression in hypopharyngeal carcinoma and clinical significa
Background.Th0 cells differentiate into Th1 or Th2 depending on multiple transcription factors acting on specific time p......
CD4+T细胞在机体抗瘤免疫反应中的作用越来越受到重视,CD4+T细胞不仅可以分泌大量的细胞因子和辅助CD8+T细胞杀伤肿瘤细胞,而且CD4+T......
h1/Th2型细胞因子分别介导细胞免疫和体液免疫,当某一型出现优势应答,则称该疾病为Th1或Th2模式。许多皮肤病(包括系统性红斑狼疮......
目的 建立荧光定量-逆转录-聚合酶链反应(FQ-RT-PCR)测定TH细胞中IL-2 mRNA和IL-4 mRNA方法,并作临床初步应用.方法制备IL-2 cDNA......
目的 观察转录因子T-bet和GATA-3在食管癌患者外周血单个核细胞(PBMC)中的表达,并探讨其与患者免疫状态的关系。方法 采用逆转录-荧光......
药对又称"对药",是临床治则治法的核心体现和复方的基本作用单位,在临床应用中被证明是行之有效的药物组合。黄芪-防风以及麻黄-甘......
变应性鼻炎(AR),中医称之为“鼻鼽”,发病率高且西药治疗存在局限,严重影响人们正常生活。研究表明Th1/Th2漂移可能是AR发病的重要因......
目的:基于Th1/Th2细胞因子失衡理论探讨中药复方清络饮对特发性肺纤维化急性加重(AE-IPF)大鼠的疗效及作用机制.方法:240只雄性Wis......
Acute graft-versus-host disease(aGVHD)is caused by allo-activated donor T cells infiltrating target organs.As a regulato......
Allergic asthma that is caused by inhalation of house dust mites(HDMs)is mainly mediated by Th2 cells.Recently,the roles......
Allergic asthma is a chronic inflammatory disease of the lung and the airway,which is characterized by aberrant type 2 i......
Expression and significance of Th1 cells,Th2 cells and Th17 cells and their related cytokines in pat
Objective To investigate the immune response characteristics of helper T cells Th1,Th2,Th17 and their related cytokines ......
目的:探讨 1,25- 二羟维生素 D3(1,25-(OH)2D3)对 ITP 模型小鼠血小板数、脾脏 T 淋巴细胞亚群 2 的影响。方法:向 20 只昆明小鼠......
期刊
干扰素调节因子4(IRF4)通过转录调控细胞分化核心转录因子及分泌型细胞因子表达,从而介导体内多种天然免疫细胞,辅助性T细胞和调节......
目的探讨瑶浴清消方(YYQXF)对急性湿疹小鼠模型的干预治疗效果及作用机制。方法 KM小鼠60只,随机分为空白组、模型组、皮肤康洗液......
目的:复发性流产(RSA)患者外周血Th1/Th2平衡与蜕膜组织中细胞凋亡、侵袭的相关性。方法:选择2015年2月-2017年12月期间在襄阳市中......
目的观察牙周炎患者外周血辅助性T1(Th1)、辅助性T2(Th2)、辅助性T17(Th17)和牙龈组织白细胞介素(IL-17)、干扰素-γ(IFN-γ)表达......
目的 观察γ射线照射对小鼠辅助性T细胞等功能亚群的影响,探讨辐射所致的免疫系统损伤在细胞学和分子水平上的机制.方法 应用细胞......
目的 探讨反复自然流产患者血清Th2细胞因子的变化。方法 采用酶联免疫吸附法检测 5 6例反复自然流产妇女血清中IL 6、IL 10的含......
目的探讨咳喘穴位敷贴对哮喘大鼠辅助性T淋巴细胞1(Th1)/辅助性T淋巴细胞2(Th2)免疫平衡的影响。方法60只雄性SD大鼠随机分为6组:......
目的 在单个细胞水平上研究类风湿关节炎 (RA)患者滑液及外周血中Th1/Th2细胞平衡状态及其与疾病活动程度的关系。方法 用酶联免......
目的:探讨红霉素对哮喘大鼠磷酸化P38及Th2类细胞因子的影响。方法:分离培养正常对照组、哮喘组、红霉素处理组大鼠的外周血单核细......
哮喘是由多种细胞和细胞组分参与的呼吸道慢性炎症性疾患。其发病机制复杂,T淋巴细胞中CD4+T细胞在哮喘的发生发展中起重要作用。......
目的研究T细胞免疫球蛋白-黏蛋白-1(TIM-1)表达对哮喘小鼠气道MUC5AC及Th2细胞因子的作用,探讨气道黏液高分泌的机制。方法30只健......
为了探讨表没食子儿茶素没食子酸酯((-)-epigallocatechin-3-gallate,EGCG)治疗实验性自身免疫性脑脊髓炎(experimentalautoimmune......