Addiction impairs cortical plasticity

来源 :第九届海内外华人神经科学家研讨会(The 9th Symposium for Chinese Neuroscientis | 被引量 : 0次 | 上传用户:zyh111111
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  We examined cortical plasticity in addicted human subjects and rats following Meth selfadministration(SA).We identified impairment of plasticity in both potentiation and depression directions in motor cortex.In addition,the motor learning behavior is disrupted in both SA animals and human addicts.The results support the psychomotor theory of addiction and the spiral theory of addiction(dorsal striatum recruitment in prolonged drug exposure).
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