Background and Objective: Osteopontin (OPN) expression is increased during the course of various chronic inflammatory diseases, including tuberculosis (TB).
Dengue virus (DENV), a member of the flavivirus genus of the Flaviviridae family, causes the most prevalent arthropod-borne viral disease of humans worldwide.
研究目的:从冷水虹鳟鱼肠道黏膜筛选抗感染益生菌株,并进行体内外抗感染免疫验证.研究方法及结果:本研究从辽宁省本溪山区半野生健康虹鳟幼鱼的肠道黏膜中分离了68株土著菌株,首先对虹鳟68株土著菌株进行体外免疫学初步评价和筛选,即运用TNF-αactivated HT29-cells and PBMCs System体外细胞模型对候选菌株进行体外筛选,结果获得了6株具有体外刺激相应细胞产生IL-8和IL
Background: Encephalomyocarditis virus (EMCV) is the causative agent of myocarditis, diabetes and reproductive and nervous system disorders in many mammalian species.
Aim: Hepatitis C virus (HCV) infection is characterized by a strong propensity toward chronicity.During chronic HCV infection, HCV core protein is implicated in dysregulating innate immune responses.
Background: The host Zinc finger antiviral protein (ZAP) has been reported exhibiting antiviral activity against positive-stranded RNA viruses (Togaviridae), negative-stranded RNA viruses (Filoviridae
Background: Innate immune responses are essential for the control of CSFV infection and are triggered through host recognition of pathogen-associated molecular patterns.
Object: Group A streptococcus (GAS) usually persist infection and lead to recurrence to the host under some condition, which is a serious problem for children and other patients.