Biomarkers相关论文
目的:评估新生血管性青光眼(NVG)闭角期患者房水内细胞因子浓度的变化并分析其与复发的关系。方法:前瞻性病例对照研究。收集2018年9......
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Study on urine biomarkers of radiation-induced injury guided by Caenorhabditis elegans as a model or
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Small molecule proteomics quantifies differences between normal and fibrotic pulmonary extracellular
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Development of heart failure risk prediction models based on a multi-marker approach using random fo
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Circulating-free DNA Mutation Associated with Response of Targeted Therapy in Human Epidermal Growth
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Mass Spectrometry-based Proteomics in Acute Respiratory Distress Syndrome: A Powerful Modality for P
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Identification of biomarkers for cervical cancer in peripheral blood lymphocytes using oligonucleoti
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Clinical implications and prognostic value of single and combined biomarkers in endometrial carcinom
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急性肾损伤(AKI)是重症患者常见的并发症,其病因复杂,发病率高,与患者的死亡率、住院时间及远期不良结局密切相关。因此,在早期可逆转阶......
目的探讨癌症基因组图谱(TCGA)分子分型在子宫内膜癌(EC)中的应用及其临床意义。方法收集2018年12月至2021年3月于北京大学人民医院行......
目的探索山东某高校新生亚健康状态(suboptimal health status,SHS)与血浆免疫球蛋白G(IgG)N-糖基组之间的相关性。方法采用病例对照研......
青光眼是一类严重的不可逆性致盲眼病,至今病因未明,诊疗效果不佳,亟需有效的早期诊断方案。近年,众多青光眼相关生物标志物被发现,为促......
目的探讨OA发病机制中潜在的Hub基因、关键miRNAs、生物过程及相关信号通路,为OA的发病机制及治疗提供生物信息学依据。方法从基因......
近年来,免疫治疗被更加频繁地用于化疗后进展的转移性胃癌,其中使用最多的是免疫检查点抑制剂(ICI)。然而ICI在不同患者中的疗效差别......
评述了目前在全世界范围内被批准紧急使用的几种新型冠状病毒肺炎(新冠肺炎)疫苗的安全性、免疫原性和有效性,以及疫苗研发和接种可......
FEZ家族锌指1反义RNA1(FEZF1-AS1)作为一种新的长链非编码RNAs(lncRNAs),在结直肠癌、胃癌、肝癌等癌症中高表达。其异常表达与癌症......
胆管癌起病隐匿,早期无明显症状,无特异性生物化学诊断指标,早期发现、早期诊断存在困难,预后不佳.随着分子生物学的进展,生物标志......
Extracellular vesicles, including exosomes and microvesicles, play a fundamental role in the activity of the nervous sys......
Bile-derived circulating extracellular miR-30d-5p and miR-92a-3p as potential biomarkers for cholang
Background: Cholangiocarcinoma (CCA) is from cholangiocytes, and therefore bile is a potentially rich source of biomarke......
目的探讨血清蛋白鉴定对克山病临床诊断与发病机制研究的价值。方法在克山病病区选择65例慢型克山病患者作为克山病(KD)组;同时以29例......
代谢组学是全面系统地描述生物样本中所有小分子代谢产物的一门学科。代谢组学可以通过内源性代谢物整体反映细胞内外环境的变化,在......
骨关节炎(OA)是一种世界性的常见病和多发病,随着人口老龄化的日益严重,OA的发病率也越来越高,是造成老年人运动障碍的首要疾病,已成为一......
长链非编码RNA(lncRNA)是非编码RNA的一种,广泛参与各种重要生命活动的调控。近年来,随着lncRNA研究的不断深入,其在肿瘤发生发展过程中......
目的探讨超声造影联合肿瘤标志物对卵巢良恶性肿瘤的诊断价值。方法回顾性分析2016年5月至2017年5月本院收治的、有完整临床资料且......
淀粉样变是一种全身性疾病,其临床表现和病理改变是淀粉样物质沉积于全身不同脏器所致。肾脏是淀粉样变最常受累的器官之一。淀粉样......
Objective:Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) is one of the cur......
目的探讨早幼粒细胞白血病蛋白(PML)和P53在食管鳞状细胞癌(ESCC)及癌前病变发生发展中的作用.方法应用组织芯片技术和免疫组织化......
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目的:探讨脑脊液腺苷脱氨酶(ADA)、乳酸(LA)、乳酸脱氢酶(LDH)、C-反应蛋白(CRP)检测对成人不同病原颅内感染的诊断价值。方法:将8......
Expression and clinical significance of miR-186 in serum exosomes of patients with chronic obstructi
Objective: To study the expression of miR-186 in serum exosomes of patients with chronic obstructive pulmonary disease, ......
Re-Exploring Biomarkers and Therapeutic Targets in Primary Melanoma Patients: Insights from Network-
Objective To identify novel biomarkers and therapeutic targets for primary melanoma using network-based microarray data ......
Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and charact......
Psoriasis is considered a systemic disease associated with metabolic abnormalities, and it is important to understand th......
Glial cell line-derived neurotrophic factor (GDNF) plays an important role in the protection of dopaminergic neurons, bu......
Identification of potential oxidative stress biomarkers for spinal cord injury in erythrocytes using
Oxidative stress is a hallmark of secondary injury associated with spinal cord injury. Identifying stable and specific o......
Objective:Upper gastrointestinal (UGI) cancers,predominantly gastric cancer (GC) and esophageal cancer (EC),are malignan......