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目的：局部进展期直肠癌的新辅助治疗标准方案是单药5-氟尿嘧啶联合放疗，但对远处转移控制不佳，增强化疗强度能否提高远处控制值得研究；另一方面，标准治疗影响患者的肛门功能和性功能，且术后的并发症发生率高，单纯新辅助化疗后选择性应用放疗也值得探索。
一项比较mFOLFOX6联合或不联合放疗新辅助治疗局部进展期直肠癌的多中心随机对照临床研究(FOWARC研究):初步结果
【摘 要】
：
目的：局部进展期直肠癌的新辅助治疗标准方案是单药5-氟尿嘧啶联合放疗，但对远处转移控制不佳，增强化疗强度能否提高远处控制值得研究；另一方面，标准治疗影响患者的肛门功能和性功能，且术后的并发症发生率高，单纯新辅助化疗后选择性应用放疗也值得探索。
【机 构】
：
广州 中山大学附属第六医院肿瘤内科 福州 福建医科大学附属协和医院胃肠外科
【出 处】
：
第十八届全国临床肿瘤学大会暨2015年CSCO学术年会
【发表日期】
：
2015年4期
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