Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：meng8500

【摘要】

：

The emergence and ongoing spread of multidrug-resistant bacteria puts humans and other species at risk for potentially lethal infections.Thus,novel antibiotics or alternative approaches are needed to

【作者】

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Yu-bin Su Xuan-xian Peng

【机构】

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State Key Laboratory of Biocontrol,School of Life Sciences,Sun Yat-sen University,University City,Gu

【出处】

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中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

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2018年10期

【关键词】

：

P cycle TCA cycle energy metabolism metabolites antibiotic resistance

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　　The emergence and ongoing spread of multidrug-resistant bacteria puts humans and other species at risk for potentially lethal infections.Thus,novel antibiotics or alternative approaches are needed to target drug-resistant bacteria,and metabolic modulation has been documented to improve antibiotic efficacy,but the relevant metabolic mechanisms require more studies.

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Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria

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