ATOMIC STRUCTURES OF THE CAPSID AND ITS ASSOCIATED TEGUMENT PROTEINS OF KAPOSIS SARCOMA-ASSOCIATED H

来源 :17th International Workshop on Kaposi’s Sarcoma Associated H | 被引量 : 0次 | 上传用户：yushu522216869

【摘要】

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Capsid-associated tegument components have been identified in alpha-and beta-herpesviruses to play essential roles in viral DNA-packaging.Whether and how such t

【作者】

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Xinghong Dai Danyang Gong Tingting Wu Ren Sun Z.H.Zhou

【机构】

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DepartmentofMicrobiology,ImmunologyandMolecularGenetics,UniversityofCalifornia,LosAngeles(UCLA),Cali

【出处】

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17th International Workshop on Kaposi’s Sarcoma Associated H

【发表日期】

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2014年7期

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Capsid-associated tegument components have been identified in alpha-and beta-herpesviruses to play essential roles in viral DNA-packaging.Whether and how such tegument components exist in gamma-herpesviruses have been a mystery.Here we report a 4(A)resolution cryoEM reconstruction of the Kaposis sarcoma-associated herpesvirus (KSHV) virion.The reconstruction reveals for the first time the structures of the capsid and capsid-associated tegument proteins at atomic details.

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